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Hypoxia‐induced alterations of G2 checkpoint regulators

Hypoxia promotes an aggressive tumor phenotype with increased genomic instability, partially due to downregulation of DNA repair pathways. However, genome stability is also surveilled by cell cycle checkpoints. An important issue is therefore whether hypoxia also can influence the DNA damage‐induced...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Hasvold, Grete, Lund-Andersen, Christin, Lando, Malin, Patzke, Sebastian, Hauge, Sissel, Suo, ZhenHe, Lyng, Heidi, Syljuåsen, Randi G.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423158/
https://ncbi.nlm.nih.gov/pubmed/26791779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.12.015
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