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Targeting lung cancer through inhibition of checkpoint kinases

Inhibitors of checkpoint kinases ATR, Chk1, and Wee1 are currently being tested in preclinical and clinical trials. Here, we review the basic principles behind the use of such inhibitors as anticancer agents, and particularly discuss their potential for treatment of lung cancer. As lung cancer is on...

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書目詳細資料
發表在:Front Genet
Main Authors: Syljuåsen, Randi G., Hasvold, Grete, Hauge, Sissel, Helland, Åslaug
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2015
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4343027/
https://ncbi.nlm.nih.gov/pubmed/25774168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00070
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