Mouse model of Epstein–Barr virus LMP1- and LMP2A-driven germinal center B-cell lymphoproliferative disease

Epstein–Barr virus (EBV) is a major cause of immunosuppression-related B-cell lymphomas and Hodgkin lymphoma (HL). In these malignancies, EBV latent membrane protein 1 (LMP1) and LMP2A provide infected B cells with surrogate CD40 and B-cell receptor growth and survival signals. To gain insights into...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Minamitani, Takeharu, Ma, Yijie, Zhou, Hufeng, Kida, Hiroshi, Tsai, Chao-Yuan, Obana, Masanori, Okuzaki, Daisuke, Fujio, Yasushi, Kumanogoh, Atsushi, Zhao, Bo, Kikutani, Hitoshi, Kieff, Elliott, Gewurz, Benjamin E., Yasui, Teruhito
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5422827/
https://ncbi.nlm.nih.gov/pubmed/28351978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1701836114
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