Protein kinase N1, a cell inhibitor of Akt kinase, has a central role in quality control of germinal center formation

Germinal centers (GCs) are specialized microenvironments in secondary lymphoid organs where high-affinity antibody-producing B cells are selected based on B-cell antigen receptor (BCR) signal strength. BCR signaling required for normal GC selection is uncertain. We have found that protein kinase N1...

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Bibliographische Detailangaben
Hauptverfasser: Yasui, Teruhito, Sakakibara-Yada, Kaori, Nishimura, Taki, Morita, Kentaro, Tada, Satoru, Mosialos, George, Kieff, Elliott, Kikutani, Hitoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529033/
https://ncbi.nlm.nih.gov/pubmed/23223530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218925110
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