Tumor-infiltrating Merkel cell polyomavirus-specific T cells are diverse and associated with improved patient survival

Tumor-infiltrating CD8(+) T cells are associated with improved survival of patients with Merkel cell carcinoma (MCC), an aggressive skin cancer causally linked to Merkel cell polyomavirus (MCPyV). However, CD8(+) T-cell infiltration is robust in only 4%–18% of MCC tumors. We characterized the T-cell...

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Detaylı Bibliyografya
Yayımlandı:Cancer Immunol Res
Asıl Yazarlar: Miller, Natalie J., Church, Candice D., Dong, Lichun, Crispin, David, Fitzgibbon, Matthew P., Lachance, Kristina, Jing, Lichen, Shinohara, Michi, Gavvovidis, Ioannis, Willimsky, Gerald, McIntosh, Martin, Blankenstein, Thomas, Koelle, David M., Nghiem, Paul
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421625/
https://ncbi.nlm.nih.gov/pubmed/28093446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-16-0210
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