Tumor-infiltrating Merkel cell polyomavirus-specific T cells are diverse and associated with improved patient survival

Tumor-infiltrating CD8(+) T cells are associated with improved survival of patients with Merkel cell carcinoma (MCC), an aggressive skin cancer causally linked to Merkel cell polyomavirus (MCPyV). However, CD8(+) T-cell infiltration is robust in only 4%–18% of MCC tumors. We characterized the T-cell...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Immunol Res
Prif Awduron: Miller, Natalie J., Church, Candice D., Dong, Lichun, Crispin, David, Fitzgibbon, Matthew P., Lachance, Kristina, Jing, Lichen, Shinohara, Michi, Gavvovidis, Ioannis, Willimsky, Gerald, McIntosh, Martin, Blankenstein, Thomas, Koelle, David M., Nghiem, Paul
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421625/
https://ncbi.nlm.nih.gov/pubmed/28093446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-16-0210
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