Amplification of distinct α-synuclein fibril conformers through protein misfolding cyclic amplification

Amyloid fibril formation has been implicated in the pathogenesis of neurodegenerative diseases. Fibrillation generates numerous conformers. Presumably, the conformers may possess specific biological properties, thus providing a biochemical framework for strains of prions. However, the precise relati...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Exp Mol Med
Main Authors: Jung, Byung Chul, Lim, Yoon-Ju, Bae, Eun-Jin, Lee, Jun Sung, Choi, Min Sun, Lee, Michael K, Lee, He-Jin, Kim, Yoon Suk, Lee, Seung-Jae
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2017
Ábhair:
Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5420798/
https://ncbi.nlm.nih.gov/pubmed/28386127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.1
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla