A Cre Transcription Fidelity Reporter Identifies GreA as a Major RNA Proofreading Factor in Escherichia coli

We made a coupled genetic reporter that detects rare transcription misincorporation errors to measure RNA polymerase transcription fidelity in Escherichia coli. Using this reporter, we demonstrated in vivo that the transcript cleavage factor GreA, but not GreB, is essential for proofreading of a tra...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Bubunenko, Mikhail G., Court, Carolyn B., Rattray, Alison J., Gotte, Deanna R., Kireeva, Maria L., Irizarry-Caro, Jorge A., Li, Xintian, Jin, Ding J., Court, Donald L., Strathern, Jeffrey N., Kashlev, Mikhail
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2017
Assuntos:
Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419468/
https://ncbi.nlm.nih.gov/pubmed/28341651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.198960
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