A Cre Transcription Fidelity Reporter Identifies GreA as a Major RNA Proofreading Factor in Escherichia coli

We made a coupled genetic reporter that detects rare transcription misincorporation errors to measure RNA polymerase transcription fidelity in Escherichia coli. Using this reporter, we demonstrated in vivo that the transcript cleavage factor GreA, but not GreB, is essential for proofreading of a tra...

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Dades bibliogràfiques
Publicat a:Genetics
Autors principals: Bubunenko, Mikhail G., Court, Carolyn B., Rattray, Alison J., Gotte, Deanna R., Kireeva, Maria L., Irizarry-Caro, Jorge A., Li, Xintian, Jin, Ding J., Court, Donald L., Strathern, Jeffrey N., Kashlev, Mikhail
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2017
Matèries:
Investigations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419468/
https://ncbi.nlm.nih.gov/pubmed/28341651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.198960
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