The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA.

Cells from patients with Cockayne syndrome (CS) are hypersensitive to UV-irradiation but have an apparently normal ability to remove pyrimidine dimers from the genome overall. We have measured the repair of pyrimidine dimers in defined DNA sequences in three normal and two CS cell strains. When comp...

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Foilsithe in:	Proc Natl Acad Sci U S A
Príomhchruthaitheoirí:	Venema, J, Mullenders, L H, Natarajan, A T, van Zeeland, A A, Mayne, L V
Formáid:	Artigo
Teanga:	Inglês
Foilsithe / Cruthaithe:	National Academy of Sciences 1990
Ábhair:	Research Article
Rochtain ar líne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54186/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2352945/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.12.4707
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