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Enzymatic activities involved in the DNA resynthesis step of nucleotide excision repair are firmly attached to chromatin.

In this study the role of nuclear architecture in nucleotide excision repair (NER) was investigated by gentle dismantling of the cell and probing the capability of chromatin to carry out repair in vitro. The rationale behind this approach is that compartmentalization of NER at nuclear structures wou...

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Detalhes bibliográficos
Main Authors: Bouayadi, K, van der Leer-van Hoffen, A, Balajee, A S, Natarajan, A T, van Zeeland, A A, Mullenders, L H
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC146546/
https://ncbi.nlm.nih.gov/pubmed/9023118
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