Insulin‐like growth factor 1 deficiency exacerbates hypertension‐induced cerebral microhemorrhages in mice, mimicking the aging phenotype

Clinical and experimental studies show that aging exacerbates hypertension‐induced cerebral microhemorrhages (CMHs), which progressively impair neuronal function. There is growing evidence that aging promotes insulin‐like growth factor 1 (IGF‐1) deficiency, which compromises multiple aspects of cere...

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Bibliografiska uppgifter
I publikationen:Aging Cell
Huvudupphovsmän: Tarantini, Stefano, Valcarcel‐Ares, Noa M., Yabluchanskiy, Andriy, Springo, Zsolt, Fulop, Gabor A., Ashpole, Nicole, Gautam, Tripti, Giles, Cory B., Wren, Jonathan D., Sonntag, William E., Csiszar, Anna, Ungvari, Zoltan
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2017
Ämnen:
Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5418199/
https://ncbi.nlm.nih.gov/pubmed/28295976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12583
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