Insulin‐like growth factor 1 deficiency exacerbates hypertension‐induced cerebral microhemorrhages in mice, mimicking the aging phenotype

Clinical and experimental studies show that aging exacerbates hypertension‐induced cerebral microhemorrhages (CMHs), which progressively impair neuronal function. There is growing evidence that aging promotes insulin‐like growth factor 1 (IGF‐1) deficiency, which compromises multiple aspects of cere...

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Publicado en:Aging Cell
Autores principales: Tarantini, Stefano, Valcarcel‐Ares, Noa M., Yabluchanskiy, Andriy, Springo, Zsolt, Fulop, Gabor A., Ashpole, Nicole, Gautam, Tripti, Giles, Cory B., Wren, Jonathan D., Sonntag, William E., Csiszar, Anna, Ungvari, Zoltan
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5418199/
https://ncbi.nlm.nih.gov/pubmed/28295976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12583
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