Hypertension-induced synapse loss and impairment in synaptic plasticity in the mouse hippocampus mimics the aging phenotype: implications for the pathogenesis of vascular cognitive impairment

Strong epidemiological and experimental evidence indicates that hypertension has detrimental effects on the cerebral microcirculation and thereby promotes accelerated brain aging. Hypertension is an independent risk factor for both vascular cognitive impairment (VCI) and Alzheimer’s disease (AD). Ho...

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Detalhes bibliográficos
Publicado no:GeroScience
Main Authors: Tucsek, Zsuzsanna, Noa Valcarcel-Ares, M., Tarantini, Stefano, Yabluchanskiy, Andriy, Fülöp, Gábor, Gautam, Tripti, Orock, Albert, Csiszar, Anna, Deak, Ferenc, Ungvari, Zoltan
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636782/
https://ncbi.nlm.nih.gov/pubmed/28664509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-017-9981-y
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