Hypertension-induced synapse loss and impairment in synaptic plasticity in the mouse hippocampus mimics the aging phenotype: implications for the pathogenesis of vascular cognitive impairment

Strong epidemiological and experimental evidence indicates that hypertension has detrimental effects on the cerebral microcirculation and thereby promotes accelerated brain aging. Hypertension is an independent risk factor for both vascular cognitive impairment (VCI) and Alzheimer’s disease (AD). Ho...

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Bibliografske podrobnosti
izdano v:GeroScience
Main Authors: Tucsek, Zsuzsanna, Noa Valcarcel-Ares, M., Tarantini, Stefano, Yabluchanskiy, Andriy, Fülöp, Gábor, Gautam, Tripti, Orock, Albert, Csiszar, Anna, Deak, Ferenc, Ungvari, Zoltan
Format: Artigo
Jezik:Inglês
Izdano: Springer International Publishing 2017
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636782/
https://ncbi.nlm.nih.gov/pubmed/28664509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-017-9981-y
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