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Two serines in the distal C-terminus of the human ß(1)-adrenoceptor determine ß-arrestin2 recruitment
G protein-coupled receptors (GPCRs) undergo phosphorylation at several intracellular residues by G protein-coupled receptor kinases. The resulting phosphorylation pattern triggers arrestin recruitment and receptor desensitization. The exact sites of phosphorylation and their function remained largel...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5417508/ https://ncbi.nlm.nih.gov/pubmed/28472170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176450 |
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