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Recruitment of β-Arrestin 1 and 2 to the β(2)-Adrenoceptor: Analysis of 65 Ligands
Beyond canonical signaling via G(α)s and cAMP, the concept of functional selectivity at β(2)-adrenoceptors (β(2)ARs) describes the ability of adrenergic drugs to stabilize ligand-specific receptor conformations to initiate further signaling cascades comprising additional G-protein classes or β-arres...
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| Publicado no: | J Pharmacol Exp Ther |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4631950/ https://ncbi.nlm.nih.gov/pubmed/26306764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.227959 |
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