FOXL2 Interacts with Steroidogenic Factor-1 (SF-1) and Represses SF-1-Induced CYP17 Transcription in Granulosa Cells

Mutations in FOXL2 are responsible for blepharophimosis-ptosis-epicanthus inversus syndrome (BPES) type I, in which affected women exhibit premature ovarian failure. FOXL2-null mice showed defects in granulosa cell development during folliculogenesis. We screened a rat ovarian yeast two-hybrid cDNA...

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Veröffentlicht in:Mol Endocrinol
Hauptverfasser: Park, Mira, Shin, Eunkyoung, Won, Miae, Kim, Jae-Hong, Go, Hayoung, Kim, Hyun-Lee, Ko, Jeong-Jae, Lee, Kangseok, Bae, Jeehyeon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2010
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417491/
https://ncbi.nlm.nih.gov/pubmed/20207836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0375
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