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Differential Apoptotic and Proliferative Activities of Wild-type FOXL2 and Blepharophimosis-ptosis-epicanthus Inversus Syndrome (BPES)-associated Mutant FOXL2 Proteins

FOXL2 is an essential transcription factor that is required for proper development of the ovary and eyelid. Mutations in FOXL2 cause an autosomal dominant genetic disorder, blepharophimosis-ptosis-epicanthus inversus syndrome (BPES). BPES type I patients have eyelid malformation and premature ovaria...

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Detalhes bibliográficos
Main Authors: KIM, Jae-Hong, BAE, Jeehyeon
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Reproduction and Development 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958583/
https://ncbi.nlm.nih.gov/pubmed/24240106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1262/jrd.2013-090
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