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Glycogen Synthase Kinase-3 Plays a Central Role in Mediating Glucocorticoid-Induced Apoptosis

It is still unclear how glucocorticoids (GCs) induce apoptosis of thymocytes and T lymphoma cells. Emergence of GC-resistant lymphoma cells is a major obstacle in GC therapy, emphasizing the need for novel strategies that maintain the sensitivity of lymphoma cells to the proapoptotic effects of GC....

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Detalles Bibliográficos
Publicado en:Mol Endocrinol
Main Authors: Spokoini, Rachel, Kfir-Erenfeld, Shlomit, Yefenof, Eitan, Sionov, Ronit Vogt
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417474/
https://ncbi.nlm.nih.gov/pubmed/20371704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0466
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