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Role of mitochondrial glucocorticoid receptor in glucocorticoid-induced apoptosis
The mechanisms by which glucocorticoid receptor (GR) mediates glucocorticoid (GC)-induced apoptosis are unknown. We studied the role of mitochondrial GR in this process. Dexamethasone induces GR translocation to the mitochondria in GC-sensitive, but not in GC-resistant, T cell lines. In contrast, nu...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118093/ https://ncbi.nlm.nih.gov/pubmed/16390935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050433 |
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