Glycogen synthase kinase-3β modulation of glucocorticoid responsiveness in COPD

In chronic obstructive pulmonary disease (COPD), oxidative stress regulates the inflammatory response of bronchial epithelium and monocytes/macrophages through kinase modulation and has been linked to glucocorticoid unresponsiveness. Glycogen synthase-3β (GSK3β) inactivation plays a key role in medi...

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Udgivet i:Am J Physiol Lung Cell Mol Physiol
Main Authors: Ngkelo, Anta, Hoffmann, Roland F., Durham, Andrew L., Marwick, John A., Brandenburg, Simone M., de Bruin, Harold G., Jonker, Marnix R., Rossios, Christos, Tsitsiou, Eleni, Caramori, Gaetano, Contoli, Marco, Casolari, Paolo, Monaco, Francesco, Andò, Filippo, Speciale, Giuseppe, Kilty, Iain, Chung, Kian F., Papi, Alberto, Lindsay, Mark A., ten Hacken, Nick H. T., van den Berge, Maarten, Timens, Wim, Barnes, Peter J., van Oosterhout, Antoon J., Adcock, Ian M., Kirkham, Paul A., Heijink, Irene H.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2015
Fag:
Call for Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652154/
https://ncbi.nlm.nih.gov/pubmed/26320152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00077.2015
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