Polarized Th1 and Th2 cells are less responsive to negative feedback by receptors coupled to the AC/cAMP system compared to freshly isolated T cells

Por Heijink, Irene H, Vellenga, Edo, Borger, Peter, Postma, Dirkje S, Monchy, Jan G R de, Kauffman, Henk F
Publicado em 2003

Interleukin-6 promotes the production of interleukin-4 and interleukin-5 by interleukin-2-dependent and -independent mechanisms in freshly isolated human T cells

Por Heijink, Irene H, Vellenga, Edo, Borger, Peter, Postma, Dirkje S, De Monchy, Jan G R, Kauffman, Henk F
Publicado em 2002

Role of aberrant metalloproteinase activity in the pro-inflammatory phenotype of bronchial epithelium in COPD

Por Heijink, Irene H, Brandenburg, Simone M, Noordhoek, Jacobien A, Slebos, Dirk-Jan, Postma, Dirkje S, van Oosterhout, Antoon J
Publicado em 2011

Protease-Activated Receptor-2 Activation Contributes to House Dust Mite-Induced IgE Responses in Mice

Por Post, Sijranke, Heijink, Irene H., Petersen, Arjen H., de Bruin, Harold G., van Oosterhout, Antoon J. M., Nawijn, Martijn C.
Publicado em 2014

A-kinase-anchoring proteins coordinate inflammatory responses to cigarette smoke in airway smooth muscle

Por Poppinga, Wilfred J., Heijink, Irene H., Holtzer, Laura J., Skroblin, Philipp, Klussmann, Enno, Halayko, Andrew J., Timens, Wim, Maarsingh, Harm, Schmidt, Martina
Publicado no Am J Physiol Lung Cell Mol Physiol (2015)

Pellino-1 Selectively Regulates Epithelial Cell Responses to Rhinovirus

Por Bennett, Julie A., Prince, Lynne R., Parker, Lisa C., Stokes, Clare A., de Bruin, Harold G., van den Berge, Maarten, Heijink, Irene H., Whyte, Moira K., Sabroe, Ian
Publicado em 2012

Airway gene expression in COPD is dynamic with inhaled corticosteroid treatment and reflects biological pathways associated with disease activity

Por van den Berge, Maarten, Steiling, Katrina, Timens, Wim, Hiemstra, Pieter S, Sterk, Peter J, Heijink, Irene H, Liu, Gang, Alekseyev, Yuriy O, Lenburg, Marc E, Spira, Avrum, Postma, Dirkje S
Publicado em 2014

Distinct radiation responses after in vitro mtDNA depletion are potentially related to oxidative stress

Por van Gisbergen, Marike W., Voets, An M., Biemans, Rianne, Hoffmann, Roland F., Drittij-Reijnders, Marie-José, Haenen, Guido R. M. M., Heijink, Irene H., Rouschop, Kasper M. A., Dubois, Ludwig J., Lambin, Philippe
Publicado no PLoS One (2017)

Prolonged cigarette smoke exposure alters mitochondrial structure and function in airway epithelial cells

Por Hoffmann, Roland F, Zarrintan, Sina, Brandenburg, Simone M, Kol, Arjan, de Bruin, Harold G, Jafari, Shabnam, Dijk, Freark, Kalicharan, Dharamdajal, Kelders, Marco, Gosker, Harry R, ten Hacken, Nick HT, van der Want, Johannes J, van Oosterhout, Antoon JM, Heijink, Irene H
Publicado em 2013

Nasal gene expression differentiates COPD from controls and overlaps bronchial gene expression

Por Boudewijn, Ilse M., Faiz, Alen, Steiling, Katrina, van der Wiel, Erica, Telenga, Eef D., Hoonhorst, Susan J. M., ten Hacken, Nick H. T., Brandsma, Corry-Anke, Kerstjens, Huib A. M., Timens, Wim, Heijink, Irene H., Jonker, Marnix R., de Bruin, Harold G., Sebastiaan Vroegop, J., Pasma, Henk R., Boersma, Wim G., Wielders, Pascal, van den Elshout, Frank, Mansour, Khaled, Spira, Avrum, Lenburg, Marc E., Guryev, Victor, Postma, Dirkje S., van den Berge, Maarten
Publicado no Respir Res (2017)

Glycogen synthase kinase-3β modulation of glucocorticoid responsiveness in COPD

Por Ngkelo, Anta, Hoffmann, Roland F., Durham, Andrew L., Marwick, John A., Brandenburg, Simone M., de Bruin, Harold G., Jonker, Marnix R., Rossios, Christos, Tsitsiou, Eleni, Caramori, Gaetano, Contoli, Marco, Casolari, Paolo, Monaco, Francesco, Andò, Filippo, Speciale, Giuseppe, Kilty, Iain, Chung, Kian F., Papi, Alberto, Lindsay, Mark A., ten Hacken, Nick H. T., van den Berge, Maarten, Timens, Wim, Barnes, Peter J., van Oosterhout, Antoon J., Adcock, Ian M., Kirkham, Paul A., Heijink, Irene H.
Publicado no Am J Physiol Lung Cell Mol Physiol (2015)