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Disruption of AMPKα1 Signaling Prevents AICAR-Induced Inhibition of AS160/TBC1D4 Phosphorylation and Glucose Uptake in Primary Rat Adipocytes

The aim of this study was to investigate the molecular mechanisms by which AMP-kinase (AMPK) activation inhibits basal and insulin-stimulated glucose uptake in primary adipocytes. Rat epididymal adipocytes were exposed to 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR) for 1 h. Subsequen...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Gaidhu, Mandeep P., Perry, Robert L. S., Noor, Fawad, Ceddia, Rolando B.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417465/
https://ncbi.nlm.nih.gov/pubmed/20501641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0502
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