Astragalus polysaccharide stimulates glucose uptake in L6 myotubes through AMPK activation and AS160/TBC1D4 phosphorylation

AIM: To establish the mechanism responsible for the stimulation of glucose uptake by Astragalus polysaccharide (APS), extracted from Astragalus membranaceus Bunge, in L6 myotubes in vitro. METHODS: APS-stimulated glucose uptake in L6 myotubes was measured using the 2-deoxy-[(3)H]-D-glucose method. T...

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Bibliographische Detailangaben
Hauptverfasser: Liu, Jian, Zhang, Jing-fang, Lu, Jin-zhi, Zhang, De-ling, Li, Ke, Su, Ke, Wang, Jing, Zhang, Ye-min, Wang, Nian, Yang, Si-tu, Bu, Lang, Ou-yang, Jing-ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086491/
https://ncbi.nlm.nih.gov/pubmed/23103623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.133
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