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Astragalus polysaccharides alleviates glucose toxicity and restores glucose homeostasis in diabetic states via activation of AMPK

AIM: To establish the mechanism underlying the improvement of glucose toxicity by Astragalus polysaccharide (APS), which occurred via an AMP activated protein kinase (AMPK)-dependent pathway. METHODS: In vivo and in vitro effects of APS on glucose homeostasis were examined in a type 2 diabetes melli...

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Bibliografiske detaljer
Main Authors: Zou, Feng, Mao, Xian-qing, Wang, Nian, Liu, Jian, Ou-Yang, Jing-ping
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007496/
https://ncbi.nlm.nih.gov/pubmed/19960007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.168
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