Chronic AMP-kinase activation with AICAR reduces adiposity by remodeling adipocyte metabolism and increasing leptin sensitivity

This study investigated the effect of chronic AMP-kinase (AMPK) activation with 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) on white adipose tissue (WAT) metabolism and the implications for visceral (VC) and subcutaneous (SC) adiposity, whole body-energy homeostasis, and hypothalamic...

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Detalhes bibliográficos
Main Authors: Gaidhu, Mandeep P., Frontini, Andrea, Hung, Steven, Pistor, Kathryn, Cinti, Saverio, Ceddia, Rolando B.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151690/
https://ncbi.nlm.nih.gov/pubmed/21737753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M015354
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