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Structure of a Thyroid Hormone Receptor DNA-Binding Domain Homodimer Bound to an Inverted Palindrome DNA Response Element

Thyroid hormone receptor (TR), as a member of the nuclear hormone receptor family, can recognize and bind different classes of DNA response element targets as either a monomer, a homooligomer, or a heterooligomer. We report here the first crystal structure of a homodimer TR DNA-binding domain (DBD)...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Chen, Yi, Young, Matthew A.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417456/
https://ncbi.nlm.nih.gov/pubmed/20610536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0129
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