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Binding of the estrogen receptor DNA-binding domain to the estrogen response element induces DNA bending.

We have used circular permutation analysis to determine whether binding of purified Xenopus laevis estrogen receptor DNA-binding domain (DBD) to a DNA fragment containing an estrogen response element (ERE) causes the DNA to bend. Gel mobility shift assays showed that DBD-DNA complexes formed with fr...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Nardulli, A M, Shapiro, D J
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364374/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1569939/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.5.2037
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