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Thyroid hormone action in the absence of thyroid hormone receptor DNA-binding in vivo
Thyroid hormone action is mediated by thyroid hormone receptors (TRs), which are members of the nuclear hormone receptor superfamily. DNA-binding is presumed to be essential for all nuclear actions of thyroid hormone. To test this hypothesis in vivo, the DNA-binding domain of TR-β was mutated within...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC171393/ https://ncbi.nlm.nih.gov/pubmed/12925699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318377 |
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