Thyroid hormone action in the absence of thyroid hormone receptor DNA-binding in vivo

Thyroid hormone action is mediated by thyroid hormone receptors (TRs), which are members of the nuclear hormone receptor superfamily. DNA-binding is presumed to be essential for all nuclear actions of thyroid hormone. To test this hypothesis in vivo, the DNA-binding domain of TR-β was mutated within...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Shibusawa, Nobuyuki, Hashimoto, Koshi, Nikrodhanond, Amisra A., Liberman, M. Charles, Applebury, Meredithe L., Liao, Xiao Hui, Robbins, Janet T., Refetoff, Samuel, Cohen, Ronald N., Wondisford, Fredric E.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 2003
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171393/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12925699/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI18377
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