Thyroid hormone action in the absence of thyroid hormone receptor DNA-binding in vivo

Thyroid hormone action is mediated by thyroid hormone receptors (TRs), which are members of the nuclear hormone receptor superfamily. DNA-binding is presumed to be essential for all nuclear actions of thyroid hormone. To test this hypothesis in vivo, the DNA-binding domain of TR-β was mutated within...

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Bibliografiska uppgifter
Huvudupphovsmän: Shibusawa, Nobuyuki, Hashimoto, Koshi, Nikrodhanond, Amisra A., Liberman, M. Charles, Applebury, Meredithe L., Liao, Xiao Hui, Robbins, Janet T., Refetoff, Samuel, Cohen, Ronald N., Wondisford, Fredric E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2003
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC171393/
https://ncbi.nlm.nih.gov/pubmed/12925699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318377
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