Both MAPK and STAT3 signal transduction pathways are necessary for IL-6-dependent hepatic stellate cells activation

BACKGROUND: During liver injury, hepatic stellate cells (HSCs) can undergo activation and transform into alpha-smooth muscle actin (αSMA)-expressing contractile myofibroblast-like cells, leading to deposition of excessive scar matrix. We have recently demonstrated that depletion of adenosine deamina...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Kagan, Polina, Sultan, Maya, Tachlytski, Irina, Safran, Michal, Ben-Ari, Ziv
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417441/
https://ncbi.nlm.nih.gov/pubmed/28472150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176173
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