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Both MAPK and STAT3 signal transduction pathways are necessary for IL-6-dependent hepatic stellate cells activation
BACKGROUND: During liver injury, hepatic stellate cells (HSCs) can undergo activation and transform into alpha-smooth muscle actin (αSMA)-expressing contractile myofibroblast-like cells, leading to deposition of excessive scar matrix. We have recently demonstrated that depletion of adenosine deamina...
में बचाया:
| में प्रकाशित: | PLoS One |
|---|---|
| मुख्य लेखकों: | , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Public Library of Science
2017
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5417441/ https://ncbi.nlm.nih.gov/pubmed/28472150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176173 |
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