ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis

Adenosine deaminase acting on RNA (ADAR) 1 binds and edits double-stranded (ds) RNA secondary structures found mainly within untranslated regions of many transcripts. In the current research, our aim was to study the role of ADAR1 in liver homeostasis. As previous studies show a conserved immunoregu...

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Foilsithe in:RNA Biol
Main Authors: Ben-Shoshan, Shirley Oren, Kagan, Polina, Sultan, Maya, Barabash, Zohar, Dor, Chen, Jacob-Hirsch, Jasmine, Harmelin, Alon, Pappo, Orit, Marcu-Malina, Victoria, Ben-Ari, Ziv, Amariglio, Ninette, Rechavi, Gideon, Goldstein, Itamar, Safran, Michal
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2016
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449086/
https://ncbi.nlm.nih.gov/pubmed/27362366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2016.1203501
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