Induction of polyploidy by nuclear fusion mechanism upon decreased expression of the nuclear envelope protein LAP2β in the human osteosarcoma cell line U2OS

BACKGROUND: Polyploidy has been recognized for many years as an important hallmark of cancer cells. Polyploid cells can arise through cell fusion, endoreplication and abortive cell cycle. The inner nuclear membrane protein LAP2β plays key roles in nuclear envelope breakdown and reassembly during mit...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ben-Shoshan, Shirley Oren, Simon, Amos J, Jacob-Hirsch, Jasmine, Shaklai, Sigal, Paz-Yaacov, Nurit, Amariglio, Ninette, Rechavi, Gideon, Trakhtenbrot, Luba
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926685/
https://ncbi.nlm.nih.gov/pubmed/24472424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8166-7-9
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados