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Regulation of Adipocyte Differentiation by Activation of Serotonin (5-HT) Receptors 5-HT(2A)R and 5-HT(2C)R and Involvement of MicroRNA-448-Mediated Repression of KLF5
Retrovirus insertion-mediated random mutagenesis was applied in 3T3-L1 preadipocyte cells to better understand the molecular basis of obesity (the expansion of individual adipocytes). We found that tryptophan hydroxylase-1, a rate-limiting enzyme for the synthesis of serotonin (5-HT), is expressed i...
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| Publicado no: | Mol Endocrinol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Endocrine Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5417392/ https://ncbi.nlm.nih.gov/pubmed/20719859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0054 |
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