MicroRNA-33 encoded by an intron of sterol regulatory element-binding protein 2 (Srebp2) regulates HDL in vivo

Sterol regulatory element-binding protein 2 (SREBP-2) transcription factor has been identified as a key protein in cholesterol metabolism through the transactivation of the LDL receptor and cholesterol biosynthesis genes. Here, we generated mice lacking microRNA (miR)-33, encoded by an intron of the...

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Detalhes bibliográficos
Main Authors: Horie, Takahiro, Ono, Koh, Horiguchi, Masahito, Nishi, Hitoo, Nakamura, Tomoyuki, Nagao, Kazuya, Kinoshita, Minako, Kuwabara, Yasuhide, Marusawa, Hiroyuki, Iwanaga, Yoshitaka, Hasegawa, Koji, Yokode, Masayuki, Kimura, Takeshi, Kita, Toru
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951399/
https://ncbi.nlm.nih.gov/pubmed/20855588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008499107
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