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βTrCP Controls GH Receptor Degradation via Two Different Motifs

The physiological roles of GH are broad and include metabolism regulation and promotion of somatic growth. Therefore, the responsiveness of cells to GH must be tightly regulated. This is mainly achieved by a complex and well-controlled mechanism of GH receptor (GHR) endocytosis. GHR endocytosis occu...

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Podrobná bibliografie
Vydáno v:Mol Endocrinol
Hlavní autoři: da Silva Almeida, Ana C., Strous, Ger J., van Rossum, Agnes G. S. H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417165/
https://ncbi.nlm.nih.gov/pubmed/22034227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1211
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