βTrCP Controls GH Receptor Degradation via Two Different Motifs

The physiological roles of GH are broad and include metabolism regulation and promotion of somatic growth. Therefore, the responsiveness of cells to GH must be tightly regulated. This is mainly achieved by a complex and well-controlled mechanism of GH receptor (GHR) endocytosis. GHR endocytosis occu...

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Bibliographic Details
Published in:Mol Endocrinol
Main Authors: da Silva Almeida, Ana C., Strous, Ger J., van Rossum, Agnes G. S. H.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2012
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417165/
https://ncbi.nlm.nih.gov/pubmed/22034227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1211
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