p53 and miR-34a Feedback Promotes Lung Epithelial Injury and Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal interstitial lung disease. The pathogenesis of interstitial lung diseases, including its most common form, IPF, remains poorly understood. Alveolar epithelial cell (AEC) apoptosis, proliferation, and accumulation of myofibroblasts and ex...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Shetty, Shwetha K., Tiwari, Nivedita, Marudamuthu, Amarnath S., Puthusseri, Bijesh, Bhandary, Yashodhar P., Fu, Jian, Levin, Jeffrey, Idell, Steven, Shetty, Sreerama
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2017
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417006/
https://ncbi.nlm.nih.gov/pubmed/28273432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.12.020
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