p53 and miR-34a Feedback Promotes Lung Epithelial Injury and Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal interstitial lung disease. The pathogenesis of interstitial lung diseases, including its most common form, IPF, remains poorly understood. Alveolar epithelial cell (AEC) apoptosis, proliferation, and accumulation of myofibroblasts and ex...

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Bibliografiske detaljer
Udgivet i:Am J Pathol
Main Authors: Shetty, Shwetha K., Tiwari, Nivedita, Marudamuthu, Amarnath S., Puthusseri, Bijesh, Bhandary, Yashodhar P., Fu, Jian, Levin, Jeffrey, Idell, Steven, Shetty, Sreerama
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2017
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417006/
https://ncbi.nlm.nih.gov/pubmed/28273432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.12.020
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