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Regulation of alveolar epithelial cell apoptosis and pulmonary fibrosis by coordinate expression of components of the fibrinolytic system

Alveolar type II (ATII) cell apoptosis and depressed fibrinolysis that promotes alveolar fibrin deposition are associated with acute lung injury (ALI) and the development of pulmonary fibrosis (PF). We therefore sought to determine whether p53-mediated inhibition of urokinase-type plasminogen activa...

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Detalhes bibliográficos
Main Authors: Bhandary, Yashodhar P., Shetty, Shwetha K., Marudamuthu, Amarnath S., Gyetko, Margaret R., Idell, Steven, Gharaee-Kermani, Mehrnaz, Shetty, Rashmi S., Starcher, Barry C., Shetty, Sreerama
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311514/
https://ncbi.nlm.nih.gov/pubmed/22140072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00099.2011
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