Calcium Signaling Regulates Trafficking of Familial Hypocalciuric Hypercalcemia (FHH) Mutants of the Calcium Sensing Receptor

Calcium-sensing receptors (CaSRs) regulate systemic Ca(2+) homeostasis. Loss-of-function mutations cause familial benign hypocalciuric hypercalcemia (FHH) or neonatal severe hyperparathyroidism (NSHPT). FHH/NSHPT mutations can reduce trafficking of CaSRs to the plasma membrane. CaSR signaling is pot...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Mol Endocrinol
Main Authors: Grant, Michael P., Stepanchick, Ann, Breitwieser, Gerda E.
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2012
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5416950/
https://ncbi.nlm.nih.gov/pubmed/23077345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1232
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares