Llwytho...

Bmp4-Msx1 signaling and Osr2 control tooth organogenesis through antagonistic regulation of secreted Wnt antagonists

Mutations in MSX1 cause craniofacial developmental defects, including tooth agenesis, in humans and mice. Previous studies suggest that Msx1 activates Bmp4 expression in the developing tooth mesenchyme to drive early tooth organogenesis. Whereas Msx1(−/−) mice exhibit developmental arrest of all too...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Dev Biol
Prif Awduron: Jia, Shihai, Kwon, Hyuk-Jae Edward, Lan, Yu, Zhou, Jing, Liu, Han, Jiang, Rulang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5416936/
https://ncbi.nlm.nih.gov/pubmed/27713059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2016.10.001
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