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Pax9 regulates a molecular network involving Bmp4, Fgf10, Shh signaling and the Osr2 transcription factor to control palate morphogenesis

Cleft palate is one of the most common birth defects in humans. Whereas gene knockout studies in mice have shown that both the Osr2 and Pax9 transcription factors are essential regulators of palatogenesis, little is known about the molecular mechanisms involving these transcription factors in palate...

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Detalhes bibliográficos
Main Authors: Zhou, Jing, Gao, Yang, Lan, Yu, Jia, Shihai, Jiang, Rulang
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833429/
https://ncbi.nlm.nih.gov/pubmed/24173808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.099028
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