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Osr1 Interacts Synergistically with Wt1 to Regulate Kidney Organogenesis

Renal hypoplasia is a common cause of pediatric renal failure and several adult-onset diseases. Recent studies have associated a variant of the OSR1 gene with reduction of newborn kidney size and function in heterozygotes and neonatal lethality with kidney defects in homozygotes. How OSR1 regulates...

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Veröffentlicht in:PLoS One
Hauptverfasser: Xu, Jingyue, Liu, Han, Chai, Ok Hee, Lan, Yu, Jiang, Rulang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956120/
https://ncbi.nlm.nih.gov/pubmed/27442016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159597
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