Mast Cells and MCPT4 Chymase Promote Renal Impairment after Partial Ureteral Obstruction

Obstructive nephropathy constitutes a major cause of pediatric renal progressive disease. The mechanisms leading to disease progression are still poorly understood. Kidney fibrotic lesions are reproduced using a model of partial unilateral ureteral obstruction (pUUO) in newborn mice. Based on data s...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Pons, Maguelonne, Ali, Liza, Beghdadi, Walid, Danelli, Luca, Alison, Marianne, Madjène, Lydia Celia, Calvo, Jessica, Claver, Julien, Vibhushan, Shamila, Åbrink, Magnus, Pejler, Gunnar, Poli-Mérol, Marie-Laurence, Peuchmaur, Michel, El Ghoneimi, Alaa, Blank, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415561/
https://ncbi.nlm.nih.gov/pubmed/28523000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00450
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