Mouse Mast Cell Protease-4 Deteriorates Renal Function by Contributing to Inflammation and Fibrosis in Immune Complex-Mediated Glomerulonephritis

Mast cells exert protective effects in experimental antiglomerular basement membrane-induced glomerulonephritis (GN), yet the responsible mediators have not been identified. In this study, we investigated the role of mouse mast cell protease (mMCP)-4, the functional homolog of human chymase, using m...

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Detalhes bibliográficos
Main Authors: Scandiuzzi, Lisa, Beghdadi, Walid, Daugas, Eric, Åbrink, Magnus, Tiwari, Neeraj, Brochetta, Cristiana, Claver, Julien, Arouche, Nassim, Zang, Xingxing, Pretolani, Marina, Monteiro, Renato C., Pejler, Gunnar, Blank, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980698/
https://ncbi.nlm.nih.gov/pubmed/20530261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902129
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