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Mast cells regulate homeostatic intestinal epithelial migration and barrier function by a chymase/Mcpt4-dependent mechanism

Altered intestinal barrier function is postulated to be a central predisposing factor to intestinal diseases, including inflammatory bowel diseases and food allergies. However, the mechanisms involved in maintaining homeostatic intestinal barrier integrity remain undefined. In this study, we demonst...

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Autores principales: Groschwitz, Katherine R., Ahrens, Richard, Osterfeld, Heather, Gurish, Michael F., Han, Xiaonan, Åbrink, Magnus, Finkelman, Fred D., Pejler, Gunnar, Hogan, Simon P.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799737/
https://ncbi.nlm.nih.gov/pubmed/20018751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906372106
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