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Mast cells regulate homeostatic intestinal epithelial migration and barrier function by a chymase/Mcpt4-dependent mechanism

Altered intestinal barrier function is postulated to be a central predisposing factor to intestinal diseases, including inflammatory bowel diseases and food allergies. However, the mechanisms involved in maintaining homeostatic intestinal barrier integrity remain undefined. In this study, we demonst...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Groschwitz, Katherine R., Ahrens, Richard, Osterfeld, Heather, Gurish, Michael F., Han, Xiaonan, Åbrink, Magnus, Finkelman, Fred D., Pejler, Gunnar, Hogan, Simon P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799737/
https://ncbi.nlm.nih.gov/pubmed/20018751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906372106
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