Identification of a New Hormone-Binding Site on the Surface of Thyroid Hormone Receptor

Thyroid hormone receptors (TRs) are members of the nuclear receptor superfamily of ligand-activated transcription factors involved in cell differentiation, growth, and homeostasis. Although X-ray structures of many nuclear receptor ligand-binding domains (LBDs) reveal that the ligand binds within th...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Endocrinol
Hauptverfasser: Souza, P.C.T., Puhl, A.C., Martínez, L., Aparício, R., Nascimento, A.S., Figueira, A.C.M., Nguyen, P., Webb, P., Skaf, M.S, Polikarpov, I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2014
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414925/
https://ncbi.nlm.nih.gov/pubmed/24552590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1359
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