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T cell therapy targeting a public neoantigen in microsatellite instable colon cancer reduces in vivo tumor growth
T-cell receptor (TCR) transfer is an attractive strategy to increase the number of cancer-specific T cells in adoptive cell therapy. However, recent clinical and pre-clinical findings indicate that careful consideration of the target antigen is required to limit the risk of off-target toxicity. Dire...
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| Опубликовано в: : | Oncoimmunology |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5414866/ https://ncbi.nlm.nih.gov/pubmed/28507809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1302631 |
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