Oncolytic measles virus encoding interleukin-12 mediates potent antitumor effects through T cell activation

Combination of oncolytic virotherapy with immunomodulators is emerging as a promising therapeutic strategy for numerous tumor entities. In this study, we developed measles Schwarz vaccine strain vectors encoding immunomodulators to support different phases in the establishment of antitumor immune re...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncoimmunology
Päätekijät: Veinalde, Rūta, Grossardt, Christian, Hartmann, Laura, Bourgeois-Daigneault, Marie-Claude, Bell, John C., Jäger, Dirk, von Kalle, Christof, Ungerechts, Guy, Engeland, Christine E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2017
Aiheet:
Original Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414860/
https://ncbi.nlm.nih.gov/pubmed/28507792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1285992
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