Oncolytic measles virus encoding interleukin-12 mediates potent antitumor effects through T cell activation

Combination of oncolytic virotherapy with immunomodulators is emerging as a promising therapeutic strategy for numerous tumor entities. In this study, we developed measles Schwarz vaccine strain vectors encoding immunomodulators to support different phases in the establishment of antitumor immune re...

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Publicat a:Oncoimmunology
Autors principals: Veinalde, Rūta, Grossardt, Christian, Hartmann, Laura, Bourgeois-Daigneault, Marie-Claude, Bell, John C., Jäger, Dirk, von Kalle, Christof, Ungerechts, Guy, Engeland, Christine E.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414860/
https://ncbi.nlm.nih.gov/pubmed/28507792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1285992
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